8 Health Benefits of Reishi Mushroom

Reishi, the “mushroom of mortality,” has been celebrated in Chinese medicine for over 4,000 years. You might be wondering if it’s right for you. Reishi mushroom, also known as Ganoderma lucidum and lingzhi, grows in hot and humid Asian regions. 

Reishi mushrooms can boost your immune system, support digestion, and enhance overall health. However, it’s important to note that they may lead to side effects and could be unsafe for individuals taking specific medications.

Let’s delve into the reishi mushroom benefits and explore their uses, optimal timing for maximum results, potential side effects, and recommended dosages.

Reishi Mushroom Benefits

1. Boosting the Immune System

One of the most renowned benefits of reishi mushroom is their ability to boost the immune system. Numerous studies have indicated that these remarkable fungi can enhance immune function. Reishi mushrooms contain compounds that stimulate the production of white blood cells, which play a crucial role in defending the body against infections and diseases. Furthermore, the anti-inflammatory properties of reishi mushrooms can contribute to an overall healthier immune system[1].

2. Cancer Prevention and Treatment

Research into the potential anticancer properties of reishi mushrooms is particularly promising. Studies have suggested that these mushrooms may have the ability to inhibit the development of certain cancers, including colorectal cancer. The compounds found in reishi mushrooms have shown potential in cancer prevention and treatment[2].

3. Reducing Fatigue and Depression

If you find yourself battling fatigue and depression, reishi mushrooms may offer a natural solution. These mushrooms have been associated with reducing fatigue and improving one’s overall quality of life. The bioactive compounds found in reishi mushrooms may alleviate symptoms of anxiety and depression, making them a valuable addition to your daily routine[3].

4. Anti-anxiety

Recent studies reveal that Reishi may have potential as an anti-anxiety treatment. Research indicates that their effects are similar to diazepam (Valium), a well-known anti-anxiety medication. Reishi possesses calming properties that are promising for anxiety management, and there’s a possibility of using reishi extracts in the development of anti-anxiety drugs. In a particular study, reishi helped alleviate anxiety and depressive behaviors in mice due to reduced inflammation in both the brain and the body[4].

5. Heart Health and Blood Sugar

Recent research suggests that reishi may have positive effects on heart health and blood sugar levels. They may help by lowering blood sugar, increasing HDL (good) cholesterol, reducing triglycerides, potentially lowering blood pressure, and thereby decreasing the risk of heart disease. These potential benefits could be particularly useful for people with diabetes or those at risk of developing it[5].

6. Diabetes Support

As mentioned above, these mushrooms have the potential to lower blood sugar levels and reduce the risk of diabetes. Studies support this, showing that reishi mushrooms may decrease blood sugar levels, boost HDL (good) cholesterol, and lower triglycerides[6].

7. Sleep Quality

Do you struggle with sleep quality? Reishi mushrooms could be the natural remedy you’ve been searching for. These fungi have been linked to improved sleep quality. By reducing stress and promoting relaxation, they can contribute to a better night’s sleep.

8. Improve Skin Health

These mushrooms pack a punch with their potent antioxidants, shielding your body from cell damage that elevates the risk of chronic diseases. But their goodness doesn’t stop there; these mushrooms also work wonders for your skin health. They house compounds that combat inflammation and boost collagen production, giving you smoother, more youthful-looking skin.


However, if you have diabetes or low blood pressure and are taking blood sugar medication, it’s crucial to consult with your doctor before adding reishi mushrooms to your routine to avoid the risk of excessively low blood sugar levels.

Reishi Medical Compounds and Its Benefits

Compound NameDescriptionPotential Health Benefits
Beta-GlucansPolysaccharides that boost immune functionEnhanced immune system support, anti-inflammatory effects
TriterpenesGanoderic acids with anti-inflammatory propertiesLiver protection, potential cancer-fighting properties
ErgosterolA precursor to vitamin DPromotes bone health, aids in calcium absorption
PolysaccharidesComplex carbohydratesImmune system modulation, potential antitumor effects
AdenosineA nucleoside with various physiological effectsBlood pressure regulation, potential anti-anxiety benefits
GanodermanontriolA compound with antioxidant propertiesProtection against oxidative stress, immune system support
Linoleic AcidA polyunsaturated fatty acidCardiovascular health, skin health, anti-inflammatory effects
Triterpene SterolsCompounds with potential cholesterol-lowering effectsCardiovascular health, cholesterol regulation
Ganoderenic AcidA compound with anti-allergic propertiesAllergy relief, potential asthma management
Polysaccharide PeptidesComplex molecules with immunomodulatory effectsImmune system enhancement, potential antitumor effects
Ganoderiol FA triterpene with anti-inflammatory propertiesPotential pain relief, anti-inflammatory effects

How to Maximize Reishi Mushroom Benefits

1. Choose High-Quality Reishi Supplements

Reishi mushrooms aren’t typically available in regular grocery stores, so many people turn to supplements. To get the most benefits, seek out high-quality, organic reishi mushroom supplements. In the next section, we’ll explore how to choose the best reishi supplements for your needs in detail.

2. Follow the Recommended Dosage

  • Dried Extract: Generally, a dosage of 1.5 to 9 grams daily is recommended.
  • Mushroom Itself: If consuming the actual mushroom, a daily dose of 25 to 100 grams is often advised.
  • Capsules: Follow the manufacturer’s recommended dosage instructions.
  • Powdered Supplements: Typically, a daily dose of 1 to 1.5 grams is suggested.

3. Combine With Other Healthy Habits

Reishi mushrooms are not a magic cure-all, and their benefits are best seen when combined with other healthy habits. Eating a balanced diet, getting regular exercise, and managing stress are all important for overall health and well-being.

4. Be Aware of Potential Side Effects

You might encounter mild stomach discomfort as a digestive side effect. Furthermore, reishi mushrooms have the potential to interact with specific medications. For individuals with bleeding issues, during pregnancy, or while taking certain medications, using reishi mushrooms may not be advisable due to potential harm.

So, if you have underlying health conditions or are on medications, it’s wise to consult a healthcare provider before considering reishi mushrooms to ensure your well-being.

Best Time to Take Reishi

To maximize the benefits of reishi mushrooms, it’s best to take them in the morning or early afternoon. Avoid taking them right before bedtime, as they could potentially induce drowsiness due to their ability to enhance sleep quality if consumed too late in the day. People often wonder how long it takes for reishi to work. Typically, noticeable effects may be experienced within a few days to a few weeks of consistent usage, though individual responses may vary.


Be patient: Reishi mushrooms are not a quick fix, and it may take some time to see their benefits. Consistency is key, so make sure to take them regularly and give them time to work.

How to Choose the Best Reishi Supplements

real mushrooms consumer number supplements

When choosing the best Reishi supplements, it’s crucial to pick the right one for maximum benefits. Here are tips on choosing the right reishi supplement:

  1. Select the Right Reishi Species: Go for supplements containing Ganoderma Lucidum, the most widely studied reishi species in supplements.
  2. Seek Hot Water Extraction: Choose supplements made using the hot water extraction method to capture the full range of health-boosting compounds in reishi.
  3. Check for Third-Party Testing: Prioritize supplements that have undergone evaluation by an independent lab to verify authenticity, potency, and ingredient accuracy.
  4. Opt for Fruiting Body Supplements: Ensure the supplement you choose contains the fruiting body of the mushroom, which holds most of the bioactive compounds. This can be used to make various products like tea, coffee, tinctures, or mushroom oatmeal.
  5. Avoid Fillers: Look for supplements that are free from unnecessary ingredients or fillers, and if possible, choose organic options for added quality.
  6. Read Reviews: Gain insights from product reviews on Amazon and the brand’s website to better understand the experiences of other users.
  7. Consult a Professional: If you’re uncertain about which supplement to choose, consider consulting a professional herbalist or a registered dietitian nutritionist to receive personalized guidance based on your specific health needs and goals.

FAQs – Reishi Mushroom Benefits

Is it OK to take Reishi every day?

Yes, it’s generally safe to take Reishi daily. It’s a natural supplement and many people use it for its potential health benefits without issues. However, it’s always wise to consult a healthcare professional before making any significant changes to your daily routine.

How does reishi make you feel?

Reishi may make you feel more relaxed and energized. It’s known for its potential to reduce stress and support overall well-being. Some people also report better sleep and improved mood when taking reishi supplements, but the effects can vary from person to person.

Does Reishi make you sleepy?

Reishi can have a calming effect and may help some people sleep better, but it doesn’t necessarily make everyone sleepy. It’s more about promoting relaxation and reducing stress, which can contribute to better sleep quality. Individual responses to reishi can vary, so it’s best to try it to see how it affects you.

How long does it take to feel the effects of reishi?

Reishi’s effects can vary. Some people report feeling benefits within a few days to a week, while others may take several weeks of consistent use. It’s essential to be patient and consistent with your reishi supplement to experience its potential effects on your overall well-being.


In conclusion, reishi mushrooms have proven to be a remarkable natural remedy with numerous health benefits. From enhancing the immune system to potentially preventing cancer and improving heart health, their advantages are vast. However, it’s essential to be aware of potential side effects and to follow recommended dosages. When chosen and used wisely, reishi mushrooms can be a valuable addition to your health routine, contributing to a happier and healthier life.


1. Effects of Ganoderma lucidum essence powder and Ganoderma Lucidum spore powder on immune function of mice with Lewis lung cancer. Retrieved from https://www.researchgate.net/publication/287101230_Effects_of_Ganoderma_lucidum_essence_powder_and_Ganoderma_Lucidum_spore_powder_on_immune_function_of_mice_with_Lewis_lung_cancer

2. International Journal of Medicinal Mushrooms. Retrieved from https://www.dl.begellhouse.com/journals/708ae68d64b17c52,58cadf0c6c913237,1af485045b17e424.html

3. Free-radical scavenging and mitochondrial antioxidant activities of Reishi-Ganoderma lucidum (Curt: Fr) P. Karst and Arogyapacha-Trichopus zeylanicus Gaertn extracts. Retrieved from https://pubmed.ncbi.nlm.nih.gov/20214017/

4. Ganoderma Lucidum Triterpenoids Improve Maternal Separation-Induced Anxiety- and Depression-like Behaviors in Mice by Mitigating Inflammation in the Periphery and Brain. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182879/

5. Reishi, Ganoderma lucidum and Ganoderma tsugae: Bioactive substances and medicinal effects. Retrieved from https://www.tandfonline.com/doi/pdf/10.1080/87559129509541025?needAccess=true

6. Reishi Mushroom. Retrieved from https://www.researchgate.net/publication/352651539_Effects_of_Powder_Extracts_and_Components_of_Ganoderma_Lucidum_in_Treatment_of_Diabetes