Lion’s Mane Powder: Before You Buy – All You Need To Know

If you’re considering Lion’s Mane powder, here’s what you should know before purchasing. Lion’s mane mushroom has a rich history in East Asian medicine and is renowned for its brain-boosting abilities. It contains bioactive compounds that offer various benefits for your body, particularly your brain, heart, and gut.

People turn to Lion’s Mane for multiple health concerns, including reducing the risk of heart disease, strengthening the immune system, and managing diabetes.

In this article, we’ll explore how you can use Lion’s Mane powder, its effectiveness, potential side effects, and important factors to consider when buying it. We’ll also share our top pick for the best Lion’s Mane powder. It’s crucial for you to have all the information you need before making your purchase.

What is Lion’s Mane Powder?

Lion’s Mane Powder is derived from the fruiting bodies of Lion’s Mane Mushrooms. These mushrooms, resembling a lion’s mane with their cascading white spines, have been utilized for centuries in traditional Asian medicine for their therapeutic qualities. The key bioactive components found in Lion’s Mane Mushrooms include beta-glucans, hericenones, and erinacines, which are believed to contribute to their health benefits[1].

Lion’s Mane Powder vs. Other Forms of Supplements

When it comes to choosing a Lion’s Mane supplement, consumers are often faced with a variety of options, including capsules, extracts, and powders. Each form has its unique characteristics, but Lion’s Mane Powder offers distinct advantages that set it apart from the rest.

1. Comprehensive Nutrient Profile

The powder is derived from the fruiting bodies of Lion’s Mane Mushrooms, ensuring that it contains the full spectrum of bioactive compounds naturally present in the mushroom. This comprehensive nutrient profile is crucial for reaping the maximum benefits of Lion’s Mane, as it retains all the essential components responsible for its health-promoting effects. In contrast, some extracts and capsules may focus on isolating specific compounds, potentially missing out on the synergistic effects of the entire mushroom.

2. Versatility in Consumption

Lion’s Mane mushroom powder’s water-soluble nature makes it highly versatile in terms of consumption. It can be mixed with a wide range of beverages, such as smoothies, tea, or coffee, without altering their taste significantly. Moreover, it can be sprinkled onto food, making it a convenient addition to your daily diet.

3. Purity: Nature in Its Truest Form

One of the defining features of the powder form is its purity. Unlike capsules or gummies, which often contain additional fillers, binders, sugar, or preservatives, Lion’s Mane Powder consists solely of Lion’s Mane Mushroom fruiting body. This purity ensures that you are getting nature in its truest form, with no unnecessary additives that might dilute the potency or quality of the supplement.

4. Full-Spectrum Benefits

As mentioned earlier, the powder captures the full range of bioactive compounds, including beta-glucans, hericenones, and erinacines, which contribute to its health benefits. These compounds work together to support brain and nervous system health, making them a comprehensive solution for cognitive enhancement.

Lion’s Mane Extract Powder Vs. Powder: Which is Better?

Lion's mane extract powder vs. powder

While Lion’s Mane Powder offers the advantage of purity, we prefer Lion’s Mane Extract Powder for its concentrated efficacy. Lion’s Mane Extract Powder is created by isolating specific bioactive compounds, resulting in a more concentrated form of Lion’s Mane supplement. This concentration can be appealing to those seeking potent, targeted benefits.

Let’s take a look at their differences with the comparison table below:

AspectLion’s Mane PowderLion’s Mane Extract Powder
Active CompoundsContains a wide range of bioactive compounds found naturally in the mushroom, including beta-glucans and hericenonesTypically standardized to contain higher levels of specific active compounds like hericenones and erinacines
BioavailabilityLower bioavailability, as the body must break down the mushroom cell walls to access nutrientsHigher bioavailability due to the extraction process, making active compounds more readily absorbed
Nutritional ContentContains various vitamins, minerals, and other nutrients naturally present in the whole mushroomMay contain fewer vitamins and minerals but higher levels of specific active compounds
Health BenefitsSupports overall health and well-being, may aid in cognitive function, immune system support, and digestive healthOften used for targeted benefits such as cognitive enhancement, nerve regeneration, and potential neuroprotective effects
PriceOften more affordable per ounce compared to extract powderTends to be more expensive due to the extraction process and higher concentration of active compounds
Suitability for Different UsesSuitable for general health support and culinary purposesPreferred for specific health goals or when higher potency is desired

Please note that the specific benefits and effects of Lion’s Mane products can vary depending on the brand, quality, and individual response. It’s essential to consult with a healthcare professional before adding any new supplements to your diet, especially if you have underlying health conditions or are taking medications.

Health Benefits of Lion’s Mane 

Lion’s Mane Mushroom boasts a plethora of health benefits, with a particular focus on enhancing brain and nervous system health. Recent studies have shed light on its remarkable potential, including stimulating the growth of brain cells and providing neuroprotective effects[2]. The mushroom’s natural compounds, such as nerve growth factor (NGF), are believed to play a pivotal role in these cognitive benefits[3].

Other potential health benefits:

  • Enhances cognitive function and memory.
  • Stimulates the production of nerve growth factor (NGF), facilitating nerve repair and regeneration.
  • Exhibits potential as an antidepressant and anxiety-reducer.
  • Boosts the immune system due to its beta-glucan content.
  • Reduces inflammation, which has links to various chronic diseases.
  • Supports gastrointestinal health by fostering beneficial gut bacteria.
  • Abounds in antioxidants, safeguarding cells from damage.
  • Aids in lowering LDL cholesterol levels.
  • Assists in managing blood sugar levels.
  • Safeguards the central nervous system and diminishes the risk of neurodegenerative diseases.
  • Displays anti-cancer properties, albeit necessitating further research.
  • Enhances cardiovascular health by mitigating risk factors such as high blood pressure.
  • Assists in appetite control and facilitates weight loss.

How to Make Lion’s Mane Powder

Making Lion's mane powder with a blender

To make Lion’s Mane mushroom powder, follow these steps:

  1. Snap your dried mushroom slices into smaller pieces and place them in your blender.
  2. Pulse the blender five to six times until the mushrooms are broken into small pieces.
  3. Blend the mushrooms on high for 30 seconds to 1 minute until they become a fine powder.
  4. Store the powder in an airtight container in a cool, dry place.

How to Use Lion’s Mane Powder

You can mix mushroom powder with your favorite drinks or sprinkle it on food because it dissolves in water, making it versatile. When you try Lion’s Mane powder for the first time, begin with a small amount to test the flavor and how your body responds. For most recipes, a quarter to half a teaspoon is a good starting point. We’ll discuss the dosage later.

Here are various ways on how to use Lion’s Mane powder:

  1. Smoothies and Shakes: Blend it with your favorite fruits, vegetables, and protein source for a nutritious morning or post-workout addition.
  2. Coffee and Tea: Enhance the flavor of your morning beverages, including hot chocolate, with a pinch of mushroom powder for a jitter-free energizing boost.
  3. Soups and Broths: Stir into chicken, vegetable, or miso soups to add a subtle mushroom flavor and boost nutrition.
  4. Baking Adventures: Use Lion’s Mane powder as a secret ingredient in muffins, bread, and pancakes by replacing a portion of the flour.
  5. Homemade Seasonings: Create unique spice blends by mixing Lion’s Mane powder with dried herbs and spices. Use this blend to season roasted vegetables, meats, or tofu for a delightful twist. If you are interested in cooking fresh Lion’s mane, you can check out our Lion’s Mane Mushroom Recipes Blog.

How Much Lion’s Mane Powder Per Day?

Determining the optimal dosage of Lion’s Mane Powder can vary from person to person. If you’re new to Lion’s Mane, start with a low dose and gradually increase it. Generally, take 250mg to 750mg per day, but consider your age and overall health for the right amount. You can take it up to three times daily, but avoid exceeding this limit.

Mix one scoop of Lion’s Mane powder with warm water, or into your tea or coffee once a day for two weeks. After that, you can increase to one or two scoops daily. So, when to take Lion’s mane? Well, think of it as an energy boost for productivity, so take it in the morning or early afternoon. You can also add Lion’s Mane powder to a breakfast smoothie or lunchtime soup for variety.

Remember, while Lion’s Mane shows promise, more human research is needed, so consult with a doctor for the right dosage for you.

What Are the Side Effects of Lion’s Mane Powder?

While Lion’s Mane Mushroom is generally considered safe for most individuals, there are potential side effects to be aware of. These may include skin irritation and digestive discomfort. It’s crucial to note that more research is needed to determine the long-term safety of Lion’s Mane Mushroom. As with any dietary supplement, it’s advisable to consult with your healthcare provider, especially if you are pregnant, breastfeeding, or taking medication.

How Long Should You Take Lion’s Mane Mushroom Powder For?

The duration for which you should take Lion’s Mane mushroom powder can vary depending on your specific health goals, individual response, and the brand of Lion’s Mane supplementation you’re using. Let’s take a look at the general guidelines you should consider:

1. Short-Term Use (Up to Several Weeks)

  • Cognitive Boost: If you’re primarily using Lion’s Mane to enhance cognitive function, memory, or focus, short-term use of a few weeks can be effective. Many people experience noticeable benefits relatively quickly.
  • Performance Enhancement: Athletes or individuals looking for a short-term performance boost may take Lion’s Mane powder before important events or competitions.

2. Long-Term Use (Several Months to Ongoing)

  • Neuroprotection: For potential long-term neuroprotective effects and overall brain health, some individuals incorporate Lion’s Mane into their daily routine over several months to years. Continuous supplementation may provide cumulative benefits.
  • Mood and Stress: If you’re taking Lion’s Mane for mood regulation or to manage stress, you might consider using it on an ongoing basis. Regular use can help maintain a balanced mood.

3. Cyclic Use

Some people choose to use Lion’s Mane in cycles, taking it for a period and then pausing before resuming. This approach can help prevent tolerance and ensure continued effectiveness.

4. Health Conditions

If you’re using Lion’s Mane for a specific health condition, consult with a healthcare professional. They can provide guidance on the appropriate duration of use based on your condition and individual needs.

5. Listen to Your Body

Pay attention to how your body responds to Lion’s Mane supplementation. Some people may find that they experience benefits quickly and only use it as needed, while others prefer to maintain a consistent daily regimen.

6. Quality Matters

The quality of the Lion’s Mane product you choose is crucial. Ensure that you select a reputable brand with high-quality, well-sourced ingredients to maximize potential benefits.

How to Choose the Right Lion’s Mane Powder For You

To make an informed choice, consider factors such as the purity, dosage, and reputation of the brand. It’s important for you to familiarize yourself with the formula to check if you have any allergies or intolerances to the ingredients. Moreover, make sure to cross-check the ingredients list to see if there could be any interactions with your prescription medication, in case you’re taking any. To address these concerns, it’s always helpful to consult with a qualified health professional. They can provide guidance tailored to your specific needs.

Where to Find the Best Lion’s Mane Supplements?

When you’re searching for the best Lion’s Mane supplements, prioritize quality and authenticity. Choose certified organic products from trusted sources, whether on Amazon or online health food shops. Opt for reliable brands that use Lion’s Mane Mushroom fruiting bodies for their supplements, without any fillers, grains, or additives. Ensure they undergo 3rd party testing to guarantee you receive the full spectrum of benefits this remarkable mushroom offers.

The Best Lion’s Mane Powder – Our Top Pick

Real Mushrooms – Organic Lions Mane Mushroom Extract Powder

Real Mushroom Lion's Mane powder


  • Support brain and immune health actively
  • Actively aid digestion and enhance mood
  • Easily ingestible
  • Affordable option
  • Actively measure beta-glucan levels
  • Certify as 100% USDA organic mushroom extract
  • Enhance absorption rates quickly
  • Completely free from grains, mycelium, additives, or fillers
  • Thousands of positive customer reviews
  • Crafted exclusively from 100% mushroom fruiting bodies


  • Taste bitter

In our opinion, Real Mushrooms Organic Lions Mane Mushroom Powder stands out as the best lion’s mane powder in 2023. Firstly, they offer exceptional affordability while maintaining excellent product quality. Secondly, they operate from a certified fulfillment center in Nevada, ensuring their lion’s mane supplement comprises solely the hot water extract of the mushroom fruit body, eliminating any fillers, mycelium, or grain. The hot water extraction method is recognized for its efficacy in extracting vital bioactive compounds from the mushroom. Notably, the mushroom’s fruiting body is the most valuable component for health purposes.

Additionally, this supplement offers a range of cognitive benefits that have been supported by studies. It has been shown to effectively reduce inflammation and enhance short-term memory, focus, concentration, and mental clarity. Moreover, it contributes to nerve health and provides a boost of mental energy during times of fatigue or stress. With its proven efficacy and absence of artificial colors, syrups, or sweeteners, this lion’s mane powder is an excellent choice.

We’re genuinely satisfied with the positive impact of this product, making it a trusted brand in our eyes.

This supplement per serving contains 1000mg of organic Lion’s Mane mushroom and 300mg of Beta-glucans.

A one-time purchase of a 60g (pack of 1) costs $29.95 ($0.49 per serving), 60 servings.

📢 SPECIAL OFFER: Subscribe for monthly Real Mushrooms delivery, save 15%!


Does powdered Lion’s Mane work?

Yes, powdered Lion’s Mane can be effective. It contains beneficial compounds that may support cognitive function and overall well-being. However, results can vary among individuals, so it’s essential to consult with a healthcare professional and follow recommended dosages for best results.

Is Lion’s Mane powder worth it?

Yes, Lion’s Mane powder can be worth it for some people. It may help with cognitive function and offer potential health benefits. However, its effectiveness varies, so it’s wise to try it cautiously, following recommended guidelines, and consult with a healthcare professional if you have concerns about its suitability for you.

Is Lion’s Mane actually good?

Yes, Lion’s Mane can be beneficial. It’s a natural supplement that may support brain health and overall well-being. Many people find it helpful, but results vary, so it’s essential to consider individual factors and consult with a healthcare expert if you have specific health concerns.

How much lion’s mane powder to take?

The recommended Lion’s Mane powder dosage varies but is typically around 500-1000 milligrams daily. However, it’s crucial to follow the instructions on the product label or consult with a healthcare professional for personalized advice based on your specific needs and health conditions. Start with a lower dose and increase gradually if needed.


In conclusion, Lion’s Mane Powder stands as a promising dietary supplement with a wealth of potential benefits for brain and nervous system health. Its natural compounds, including nerve growth factor (NGF), make it a standout choice for those seeking cognitive enhancement. 

As you embark on your journey to harness the Lion’s Mane Powder, remember that individual experiences may vary. It’s crucial to prioritize quality and authenticity when selecting a supplement, ensuring that you receive the full range of health benefits this remarkable mushroom has to offer.


1. The Inhibitory Effects of Hericium erinaceus β-glucan on in vitro Starch Digestion. Retrieved from

2. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model. Retrieved from

3. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Retrieved from